Palo Azul: All Health Benefits

palo azul all health benefits

After thousands of hours of research, we compiled every single medical study about palo azul's health benefits in this article. This way, you can learn everything that the magical palo azul can do for your health. 

palo azul and fruits with flavonoids

 


    Let's get straight to it then! And don’t forget to help your friends & family by sharing palo azul with them! 

    book with palo azul benefits and studies

     

    Summary

    palo azul antioxidant

    Antioxidant

    • Detox your body and fight free radicals that cause oxidative stress

     

    palo azul anti-inflammatory

    Anti-inflammatory

    • Improve joint health and wellness
    • Relieves sciatic nerve pain and arthritis

     

    palo azul flavonoids

    Flavonoids

    • Lower your cholesterol
    • Reduce your risk of diabetes, cardiovascular disease, hypertension and atherosclerosis

       

      palo azul diuretic

      Diuretic

      • Cleanse your body from toxins and promote kidney & urinary tract health
      • Prevents and reduces kidney stone growth

       

      palo azul antidiabetic

      Anti-diabetic

      • Improves your insulin sensitivity and reduces blood glucose level

       

      palo azul antiviral antibacterial

      Antiviral and Antibacterial

      • Protects against cavities, toothache, gum diseases, bad breath, and E. coli
      • Relieves abdominal pain, nausea, and diarrhea

       

      Now you see why we call it MagikTea?

       

       

       

      Health Benefits of Palo Azul

      palo azul antioxidant

      Antioxidant

      Palo azul’s antioxidant property is among its most studied and most prominent benefits. 

      In fact, we reviewed over a dozen studies whose results concluded that palo azul exhibited an antioxidant effect, and many of these also found anti-inflammatory effects (we will cover these next). Some of these studies found compounds in palo azul such as dihydrochalcone and methanol which induce powerful antioxidant and anti-glycation activities. 


      Antiinflammatory and antioxidant foods: vegetables, fruits, nuts, seeds, fatty fish, olive oil, turmuric, cocoa and teas such as palo azul

      palo azul and fruits with flavonoids

      What is anti-glycation? 

      The anti-glycation property protects against AGEs (advanced glycation end products), which are harmful compounds that are considered to play an important role in the process of aging and in degenerative diseases such as diabetes, cancer, Alzheimers, and others. This is why you should be eating your vegetables, fruits, and drinking your tea every day!

      If you were wondering what antioxidants are… They are compounds such as vitamins or phytochemicals like carotenoids or flavonoids which inhibit oxidative stress. They protect tissue of damage from free radicals and because of this, they prevent inflammatory responses before they can even take effect. 

      What is oxidative stress?

      oxidative stress

      Oxidative stress is an imbalance between free radicals and antioxidants in the body.

      What are free radicals?

      Free radicals are atoms with a single valence electron that cause damage to the body associated with diabetes, cancer, aging, atherosclerosis, Parkinson's, Alzheimer's and many other diseases.

      free radicals and oxidative stress formation

      This happens because electrons like to be in pairs... and for this reason, free radicals look for "free" electrons in the body. This causes damage to cells, proteins, DNA and these damaged molecules can mutate, grow tumors, and damage the DNA code. Eventually, this cellular damage causes new cells to grow with defects and it will lead to aging and degenerative diseases. 


      How can antioxidants help you?

      They help you lose weight

      woman losing weight with palo azul

      One study analyzed 2754 twins and found that the group that consumed the most flavonoids:

      • Had less percentage of fat
      • Burned more fat in the abdomen

      Specifically, the researchers found that the twins with the highest consumption of flavonoid-rich foods (onions, tea, apples, pears, and cocoa) “had a 3-9% lower FMR (fat mass ratio) than that of their co-twins.”

      Moreover, the researchers found that the “women who ate a lot of flavonoid-rich foods had a lower percentage of body fat than women who ate less. The amount of abdominal fat also differed significantly between the two groups.”

      The researchers of this study also point out that “It is important to note that abdominal fat is an important risk factor for diseases such as type 2 diabetes and heart problems.”

      girl losing weight palo azul

       

      Another study looked at 124,000 people and found that "flavonoids increase energy expenditure, decrease fat absorption and function as anti-inflammatories. The researchers in this same study found that "increased consumption of most flavonoid subclasses was associated with reduced weight gain.” 

      They also mentioned that the participants that consumed more flavonoids maintained their weight better and even lost some weight and they concluded the following:

      "Our results suggest that choosing fruits and vegetables that are high in flavonoids, such as apples, pears, berries and peppers, can help with weight control." 

       

      They promote healthy skin

      woman with antioxidant skin cream

       

      Victoria Lewis, a doctor of dermatology mentions that “antioxidants are often considered the fountain of youth by skin-care professionals and experts.”

      “Not only do they (antioxidants) scavenge free radicals—the number one skin-aging culprits—to promote a brighter, more even complexion, they’re also the superstars at nixing fine lines and keeping skin looking fresh.”

      This is due to its ability to eliminate oxidative stress and free radicals, which are “the number one skin-aging culprits.” 

      This oxidative stress causes damage to our cells, and this damage  eventually leads to aging and wrinkles in our skin. 

      Another doctor of dermatology, Dr. Mack, writes that “antioxidants protect your skin from this (oxidative stress) and help reduce pigmentation and fine lines and wrinkles.” He goes on to mention that in his opinion, “an antioxidant serum is a must for your skin-care routine.”

      For this reason, many pharmaceutical and cosmetic companies supplement their skin care products with tea extracts!

       

      They "decrease cancer promoting action"

      woman with cancer

      We read two medical reviews composed of findings from 327 studies done specifically on flavonoids, and found that oxidative stress can lead to cancer, diabetes, cardiovascular disease, and aging ... For this reason, they found that antioxidants show potential to fight these diseases. 

      Therefore, "diets rich in antioxidants decrease the cancer-promoting action of free radicals and oxidative stress." One of the studies we reviewed found that fruits and vegetables that have flavonoids have been reported as cancer chemopreventive agents and are inversely associated with cancer incidence.

      palo azul vs cancer

      * Here’s a very interesting fact for wine drinkers: “Moderate wine drinkers also seem to have a lower risk to develop cancer of the lung, endometrium, esophagus, stomach, and colon.”

      Thank you flavonoids!

      wine reduces risk of cancer

      We also read a study that recruited 1522 breast cancer cases and 1547 frequency control subjects from June 2007 to July 2018 in Guangdong, China. The results of this study indicated that consumption of “flavonoids and most flavonoid subclasses intakes were inversely associated with breast cancer risk.”

      Finally, “the critical relationship of fruit and vegetable intake and cancer prevention has been thoroughly documented. It has been suggested that major public health benefits could be achieved by substantially increasing consumption of these foods.”

      In other words... oxidation in our body leads to cancer and other diseases, therefore we should consume lots of antioxidants to stay healthy.

       

      palo azul flavonoids

      Flavonoids

      At this point you're probably dying to know... What the heck flavonoids!?

      Flavonoids are natural products found in vegetables, fruits, plants, bark, flowers, wine and teas like Palo Azul.

      There’s been literally hundreds of studies that have found a ton of health benefits which are attributed to their "antioxidant, anti-inflammatory, anti-diabetic, anti-aging, anti-hypertensive, anti-bacterial, anti-mutagenic, anti-viral and anti-cancer properties."

       
      palo azul and fruits with flavonoids

       

      For example, numerous epidemiological studies show an “inverse correlation between dietary flavonoid consumption and chronic degenerative diseases, such as cardiovascular diseases, diabetes, osteoporosis, neurodegenerative diseases, and cancers.”

      According to a medical review, flavonoids’ powerful health benefits have made them “an indispensable component in a variety of nutraceutical, pharmaceutical, medicinal and cosmetic applications.

      These are the most flavonoid-rich foods: apples, pears, onions, strawberries, blueberries, celery, peppers, and teas such as palo azul

      applepearsonionsstrawberries and blueberriescelerypalo azul tea

       

      This is the reason why we should be eating vegetables, fruits, and drinking palo azul tea every day :)


      How can flavonoids help you?

      Lower your cholesterol

      eggs cholesterol
       

      One study done on flavonoids concluded that “flavonoids in tea may lower blood cholesterol concentrations and blood pressure, thereby providing some protection against cardiovascular disease.”

      Another study found that the antioxidant property of flavonoids " inhibits the oxidation of LDL cholesterol.”

      Finally, another study concluded that: “Palo azul (EP) reduced the blood glucose, increased serum insulin, body weight, marker enzymes of hepatic function, glycogen, HDL, GK and HK while there was reduction in the levels of triglyceride, cholesterol.”

       

      Reduce risk of cardiovascular disease

      palo azul vs cardiovascular disease

      Epidemiological, clinical and animal studies reveal that “flavonoids may exert protective effects against various disease conditions including cardiovascular disease and cancer.”

      Other population studies have demonstrated that “flavonoid intake is inversely correlated with mortality from cardiovascular disease.”

      Researchers also found that flavonoids may lower blood cholesterol concentrations and blood pressure, thereby providing some protection against cardiovascular disease.”

      Finally, a study concluded the following:

      "Antioxidant, antithrombotic, anti-inflammatory, and hypolipidemic properties play a significant role in the lower cardiovascular mortality illustrated by increased flavonoid consumption.”

       
       

      Reduce risk of atherosclerosis

      butter atherosclerosis

      Various epidemiological studies show that “flavonoids in tea may lower blood cholesterol concentrations and blood pressure, thereby providing some protection against cardiovascular disease.”

      This is due to its ability to "inhibit the oxidation of LDL through a mechanism involving the elimination of free radicals that plays a key role during atherosclerosis.”

      One study established the importance of the oxidation of LDL cholesterol by writing that “oxidative modification of LDL cholesterol is thought to play a key role during atherosclerosis.”

      *Here comes an extremely important finding!

      Scientists in one study observed the “consumption of them (flavonoids) is associated with improvement in endothelial function (blockage of arteries) via vascular endothelial nitric oxide synthase and protein kinase B (Akt) activation.”

       

      What is endothelial function?

      The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction, as well as enzymes that control blood clotting, immune function, and platelet adhesion.

      palo azul vs endothelial dysfunction or clogged arteries
       

      Endothelial dysfunction has been shown to be important in predicting stroke and heart attacks due to the inability of the arteries to dilate completely. Dysfunction can result from high blood pressure, diabetes, high cholesterol, and smoking.

      Studies have shown that endothelial dysfunction precedes the development of atherosclerosis, a chronic disease characterized by abnormal thickening and hardening of the artery walls. This can cause a stroke or a heart attack.

      In other words...

      Endothelial dysfunction causes a blockage in the arteries that can lead to hypertension, stroke, or heart attack. This is why you should take care of your cholesterol levels by consuming flavonoid-rich foods and eliminating inflammatory and oxidative foods!

      We already shared a list of flavonoid-rich foods which you should definitely include in your diet. The following are some of the most powerful anti-inflammatory and antioxidant foods on the planet.

      Antiinflammatory and antioxidant foods: vegetables, fruits, nuts, seeds, fatty fish, olive oil, turmuric, cocoa and teas such as palo azul

      palo azul and antiinflammatory foods

      Inflammatory and oxidative foodsfoods that are heavily processed and have high fructose content, trans fats and refined carbs

      hamburger and fries lead to oxidative stress

       

      Reduce your risk of Hypertension

      man with hypertension
       

      We’ve read two medical reviews composed of findings from 327 different studies conducted specifically on flavonoids, and their findings revealed that "dietary flavonoids are associated with a lower risk of hypertension and CVD (cardiovascular disease).”

      The scientists who published these reviews also observed that “the blood pressure level was reduced in patients with hypertension” after greater consumption of flavonoids. 

      Finally, one study concluded the following: 

      “Flavonoids in tea may lower blood cholesterol concentrations and blood pressure, thereby providing some protection against cardiovascular disease.”



      Reduce your risk of Alzheimer's, Parkinson's, and Dementia

      man with alzheimers parkinsons or dementia
       

      A very interesting study analyzed a group of 49,281 men and 80,336 women in the Health Professionals Follow-up Study and found that “the participants in the highest quintile of total flavonoids had a 40% lower PD (Parkinson’s Disease) risk than those in the lowest quintile.” The researchers from this study concluded the following:

      “Our findings suggest that intake of some flavonoids may reduce PD (Parkinson's Disease) risk.”

      Another study found that flavonoids have “favourable biochemical and antioxidant effects associated with various diseases such as cancer, Alzheimer's disease (AD), atherosclerosis, etc.”

      Finally, a study concluded the following:

      “Flavonoids contained in berries may have a positive effect against Parkinson's disease and may help to improve memory in elderly people. Intake of antioxidant flavonoids has been inversely related to the risk of incidence of dementia.”



      Reduce risk of erectile dysfunction

      man with erectile dysfunction

      Results from one study "showed that “flavonoid consumption 50 mg/day reduced the risk of erectile dysfunction by 32%.” 

      Another study found similarly that "flavonoid-rich foods are associated with a reduced incidence of erectile dysfunction.” 

      Additionally, one study found that "men with erectile dysfunction reported a lower monthly average of total flavonoid intake." 

      Due to the antioxidant capacity of flavonoids, another study concludes that flavonoids "may ameliorate erectile dysfunction by inhibiting oxidative stress."

       

       

      palo azul anti-inflammatory

      Anti-inflammatory

      This is another one of palo azul’s most beneficial health properties! Considering that it is responsible for improving your sciatic nerve health, reducing back pain and arthritis pain.

      Results from 6 different studies concluded in their results that palo azul induced a significant inhibition of inflammation and/or showed anti-inflammatory activity.

      omega 3 antiinflammatory and flavonoids

      How can anti-inflammatories help you?


      Reduce sciatic nerve pain

      woman with sciatic nerve pain
       

      The main reason for sciatic nerve pain is commonly attributed to the accumulation of uric acid in the blood and palo azul is an active reducer of uric acid levels. Inflammation is another common cause of sciatic nerve pain and we have already discovered that palo azul is a powerful anti-inflammatory. For these 2 reasons, palo azul has been traditionally used for centuries to cure sciatic nerve pain and also joint pain.

      woman healing sciatic nerve pain
       

      One medical study concluded the following: "The inhibition (of inflammation) leads to a reduction in pain behavior and inflammation following chronic constriction injury (CCI) of the sciatic nerve."

      Another medical article mentions that “any cause of irritation or inflammation of the sciatic nerve can produce the symptoms of sciatica.”

      In addition to this, one study found mentions that “the plant (palo azul) has been used in traditional treatments of nephrolithiasis or urolithiasis [2], lumbalgia, arthritis, rheumatism, sciatica, and as blood depurative because it eliminates uric acid, of which application the palo azul derives its diuretic and antirheumatic fame.”


      Reduces back pain and arthritis

      woman with back pain

      Various studies have found that flavonoids and palo azul’s antiinflammatory capacities are effective for treating arthritis and pain management.

      One study found that “the ethanol extract of palo azul and its flavonoids-rich fractions “inhibited secondary inflammatory reactions in arthritic rats.”

      The researchers also found that many plant constituents, including flavonoids, have proven effective against arthritis by reducing cartilage degradation, diminishing leukocyte infiltration in the synovial space, decreasing serum cytokine levels, and other mechanisms (9)."

      Finally, one study concluded the following: “Our findings support the use of Eysenhardtia polystachya bark (palo azul) for the treatment of rheumatoid arthritis and pain management.”




      Reduce joint pain

      woman with arthritis

      A common cause of joint pain is inflammation, and we already know that palo azul is a powerful anti-inflammatory.

      In addition to this, a study found that flavonoids (found in vegetables, fruits and teas like palo azul) “have the most potential of dietary components for promotion of bone health beyond calcium and vitamin D.”

      This finding is supported by population studies which have shown “flavonoid consumption to have a stronger association with bone than general fruit and vegetable consumption.”

      palo azul strengthens joint health

       

       

      palo azul diuretic

      Diuretic

      Palo azul has been used for over 300 years for its diuretic efficacy; which essentially means that it flushes out your system and makes you urinate. Palo azul was even transported to Europe after the discovery of America for its diuretic efficacy.

       

      Here’s a fun fact…Due to its diuretic efficacy, palo azul is commonly used by people as a means to clean out their system in order to pass drug tests. 

      In fact...In fact, diuretics are so powerful in cleansing the body, that in 1988 they were banned by the World Anti-Doping Agency because athletes were using them to detoxify their bodies and pass drug tests!

      How can diuretics help you?

      Alleviate kidney pain and reduce kidney stone growth

      kidney stones

      Due to its popularity as a diuretic, many studies have evaluated its diuretic activity and its efficacy for treating kidney pain and kidney stones. 

      Various studies have found that palo azul shows effective diuretic & antibacterial activity and therefore, it significantly reduces kidney stone growth and alleviates kidney pain.

      palo azul vs kidney stones

      In fact, 6 different studies found that palo azul prevented the formation of kidney stones (calcium oxalate crystals) and significantly decreased the size of kidney stones. Therefore, one study concluded that it can be “recommended as a preventative medicine in renal stone (kidney stone) formation.”

      But that’s not all! Another study revealed that "flavonones in palo azul have been identified with antibacterial and antifungal activity.” Therefore, it could be used for “kidney problems, urinary tract pain, kidney calculi, and as a deflamatory."

      palo azul vs bacteria


      KEY FINDINGS

      • “The aqueous extract of E. polystachya (palo azul) "induced an important diuretic activity" because increases in urinary flow and urinary sodium excretion were observed.

      • Researchers from one study “found that the isolated isoflavones in Palo Azul stopped the formation of calcium oxalate crystal growth in rats.”

      • Isoflavones from palo azul “significantly lower(ed) growth rate and nucleation rate of calcium oxalate crystals” and “work as inhibitors in the formation and crystal growth of COM and phosphate and may protect against stone formation by reducing the degree of aggregation and the size of particles precipitated.”


        Alleviates urinary tract pain

        woman with urinary tact or kidney pain

        Palo azul's diuretic property is also effective in treating urinary tract pain, because it increases urinary flow.

        The results of 4 different studies suggest that palo azul can "reduce irritability in the urinary tract."

        In addition, the methanolic extracts of palo azul were effective against bacteria which are “the most frequent causal agents of urinary tract infection.”

        palo azul antioxidant herbs and plants
         

        A book about botanical medicine writes the following statement about palo azul:

        “If prone to acidic, overly concentrated urine, associated kidney stones and urinary tract sediment then Kidneywood (palo azul) will be of use. Because of the plant’s alkalinizing nature, acidic precipitants dissolve back into the urine, thereby reducing pain and urinary tract irritability associated with lithic deposits. Kidney wood (palo azul) is soothing to kidney and urinary tract irritability.”


        KEY FINDINGS

        • “Due to the alkalinizing nature of this plant, acidic precipitants dissolve back into the urine, thus reducing pain and irritability of the urinary tract.” 

        • “The bark of E. polystachya (palo azul) induces an increase on urinary excretion of water and sodium, similar to furosemide, but with the advantage of a potassium-saving effect. These findings support the claims of diuretic efficacy of the bark of E. polystachya (palo azul) in the Mexican Traditional Medicine.”


          palo azul antidiabetic

          Anti-diabetic

           

          Various studies have found that extracts from palo azul “significantly reduced blood glucose levels” and showed “good anti-diabetic activity.” In fact, 3 different studies have found that palo azul can improve insulin sensitivity, insulin secretion, glucose metabolism and/or increase muscle mass.

          One study in particular concluded the following: “The results indicate that EP (palo azul) has good antidiabetic activity and therefore could be used to prevent the development of diabetes.”

          In addition, it is well documented that oxidative stress can cause cancer, diabetes, cardiovascular disease, and aging. Therefore, antioxidants such as palo azul can “interfere with radical-producing systems and increase the function of endogenous antioxidants, protecting the cells from damage by these free radicals.”

          palo azul herbs and antioxidants

          Palo azul also contains flavonoids and “numerous epidemiological studies show an inverse correlation between dietary flavonoid consumption and chronic degenerative diseases, such as cardiovascular diseases, diabetes, osteoporosis, neurodegenerative diseases, and cancers.”

          One study even found that in a large cohort of women, a clinical trial has shown that "flavonoids are protective against type 2 diabetes.”

           

          KEY FINDINGS

          • Several medical studies found that extracts from palo azul "significantly decreased blood glucose levels" and showed "good anti-diabetic activity.”

          • “Palo azul increased the expression of insulin-sensitizing adipokine, adiponectin, which is a direct target of PPARγ.”

          • “In conclusion, palo azul may increase muscle mass in the body and improve insulin resistance conditions by facilitating the formation of myotubes by promoting myocyte differentiation.”

          • “Chalcones, flavonoids, and dihydrochalcones in palo azul “promote pancreatic β-cell survival, insulin secretion-enhanced hyperglycemia, and hyperlipidemia in glucose-induced diabetic zebrafish.” Finally, the researchers concluded that these findings suggest that EP/AgNPs could be used as therapeutic nanoparticles to prevent the development of diabetes.”

          • “In addition, flavonoids have a role in the treatment of diabetes by virtue of their ability to protect against hyperglycemic and alloxan-induced oxidative stress in experimental animal models.”

           

          palo azul antibacterial

          Antiviral & Antibacterial

          A medical review which analyzed the results of 161 studies mentioned that flavonoids proved to be "potent antimicrobial and viral inhibitors."

          Therefore, they are found to be effective against many infectious diseases (bacterial and viral) such as E. coli.

          We also read a very interesting study which tested 47 different plants for the treatment of dental diseases such as toothache, dental caries, periodontal disease and gingivitis. 

          As it turns out, palo azul was among the plants that showed the highest inhibitory effect against certain bacterial diseases! For this reason, it was among the plants most frequently used for treating tooth pain, gum diseases, cavities, and bad breath.

          woman with perfect teeth

          Another study even found that it “showed good antimicrobial effects in E. coli." 

          * Here is an interesting finding:

          “Flavonoids are known to be synthesized by plants in response to microbial infection; thus it should not be surprising that they have been found in vitro to be effective antimicrobial substances against a wide array of microorganisms.” It’s due to their potent antibacterial, antimicrobial and antiviral activity that flavonoids “show inhibitory activity against E. coli."

          palo azul vs bacteria

          Finally, book about botanical medicine writes the following statement about palo azul:

          “Flavonoids have also been recognised for their antimicrobial activity and many researchers have isolated and identified the structures of flavonoids having properties of antifungal, antiviral and antibacterial activity. Because of this property, many flavonoids are now being used extensively in the fields of nutrition, food safety and health.

           

          KEY FINDINGS

          • One study tested 47 plants and concluded the following: “Our study demonstrated that most of the medicinal plants showed an antibacterial effect in vitro, and justified at least in part their use in traditional medicine.”

          • The same study mentioned that “the most frequent uses were to treat tooth pain, gum diseases, bad breath and cavities.”

          • Moreover, this same study found that Eysenhardtia polystachya (palo azul) was among the plants that showed the “highest inhibitory effect against Streptococcus mutans and Porphyromonas gingivalis.”

          • Another study found that palo azul “showed good antimicrobial effects in E. coli” and concluded the following: “The results here presented corroborate the folk medicinal use of Eysenhardtia polystachya (palo azul) in the treatment of infections, diarrhea, inflammation, and pain.

           

            Anti-viral

            mona lisa drinking palo azul

            Another medical review which reviewed 166 studies mentions "many flavonoids show activity against several types of virus including HSV, respiratory syncytial virus, polio virus and Sindbis virus [135].”

            * Here is another interesting finding:

             One study mentioned that flavonoids “are an important source for the discovery and the development of novel antiviral drugs.

             

            What types of viruses can flavonoids block?

            Recently, we found a study published in 2020 which found that “flavonoids block attachment and entry of viruses into cells, interfere with various stages of viral replication processes or translation and polyprotein processing to prevent the release of the viruses to infect other cells.”

            The researchers mention that “flavonoids are natural biomolecules that are known to be effective antivirals” and that “these biomolecules can act at different stages of viral infection, particularly at the molecular level to inhibit viral growth.” They found that flavonoids have inhibitory effects against Ebola, herpes, HIV, Influenza and coronaviruses.

            palo azul vs virus antiviralpalo azul vs coronaviruspalo azul vs hiv viruspalo azul vs influenza viruspalo azul vs herpes ebola

            Lastly, the researchers mention that due to flavonoids’ ability to target various stages of viral infection, they are “becoming a more focused topic to explore their potential as antivirals in the current era.”

            For all these reasons, flavonoids are used to develop new antiviral drugs.


            KEY FINDINGS

            • “Flavonoids have also been recognised for their antimicrobial activity and many researchers have isolated and identified the structures of flavonoids having properties of antifungal, antiviral and antibacterial activity.”

            • “Naturally occurring flavonoids with antiviral activity have been recognized since the 1940s and many reports on the antiviral activity of various flavonoids are available.”

            • “The antiviral effect of flavonoids has been shown by Wang et al.(,142), particularly in therapy for viral infection.”

            • “Inhibition of viral polymerase and binding of viral nucleic acid or viral capsid proteins have been proposed as antiviral mechanisms of action [139].”




              palo azul antinociceptive

              Antinociceptive

              Several studies have shown that palo azul has antinociceptive properties. What does this mean? Antinociceptives block the detection of a painful or harmful stimulus by sensory neurons. 

              In other words... they inhibit the sensation of pain by blocking signals from neurons. Popular examples of antinociceptives include general anesthesia and morphine.

              One study mentioned that palo azul “decreased the serum levels of pro-inflammatory cytokines and showed antinociceptive activity. These findings support the use of Eysenhardtia polystachya in Mexican folk medicine for treating rheumatoid arthritis and pain management.

              Another study found that palo azul “showed antinociceptive and antidiarrheal effects with similar potency compared to standard drugs.”

              * Although we do not recommend replacing standard medications, these findings establish the importance of having a diet full of natural medicines with potent health benefits. 

              For these reasons Palo Azul has been used traditionally for centuries to treat conditions such as arthritis, rheumatism, lumbago, gout and sciatica.


              KEY FINDINGS

              • “We evaluated the anti-arthritic and antinociceptive properties of an ethanolic extract of E. polystachya (palo azul) bark and its rich-flavonoids fractions in murine models. Many plant constituents, including flavonoids, have proven effective against arthritis by reducing cartilage degradation, diminishing leukocyte infiltration in the synovial space, decreasing serum cytokine levels, and other mechanisms (9)."

              • “Eysenhardtia polystachya (palo azul) also decreased the serum levels of pro-inflammatory cytokines IL-6, TNF-α, and GM-CSF and showed antinociceptive activity at the peripheral and central levels, which suggests that this plant has an effect on the cellular immune response.” 

               

              palo azul tea

              This concludes our list of all health benefits of palo azul tea! We know it was a bit long, but we hope it was worth your time and we hope that this helps you make healthier lifestyle choices. 

               

              magiktea palo azul logo

              Don't keep this to yourself though...

              help us #SharetheMagik of palo azul with your loved ones!

               



              Medical Studies

              Now you can see we’re not kidding when we say we’ve studied Palo Azul for over 1000 hours!

              *Note: Palo Azul is commonly referred by its scientific name: Eysenhardtia polystachya / E. polystachya / E.P  or Cyclolepis genistoides / C. genistoides

               

              Anti-Oxidant & Anti-Inflammatory

              (Apr-Jun, 2014) Evaluation of antidiabetic, antioxidant and antiglycating activities of the Eysenhardtia polystachya

              (Sept 8, 2018) Silver Nanoparticles Synthesized Using Eysenhardtia polystachya and Assessment of the Inhibition of Glycation in Multiple Stages In Vitro and in the Zebrafish Model 

              (June 8, 2016) Properties of Flavonoids Isolated from the Bark of Eysenhardtia polystachya and Their Effect on Oxidative Stress in Streptozotocin-Induced Diabetes Mellitus in Mice

              (Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models

              (May 1, 2018) Protection of silver nanoparticles using Eysenhardtia polystachya in peroxide-induced pancreatic β-Cell damage and their antidiabetic properties in zebrafish 

              (Dec 1, 2011) SEPARACIÓN Y EVALUACIÓN DEL EFECTO ANTIINFLAMATORIO Y ANTIOXIDANTE DE LOS FLAVONOIDES DE Eysenhardtia polystachya (Ort.) Sarg.

              (March 28, 2019) 3-O-β-d-glucopyranosyl-α,4,2,4,6-pentahydroxy-dihydrochalcone, from Bark of Eysenhardtia polystachya Prevents Diabetic Nephropathy via Inhibiting Protein Glycation in STZ-Nicotinamide Induced Diabetic Mice 

              (Summer, 2018) Silver nanoparticles synthesized with a fraction from the bark of Eysenhardtia polystachya with high chalcone and dihydrochalcone content effectively inhibit oxidative stress in the zebrafish embryo model 

              (Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models 

              (Feb 29, 2015) Evolution of anti-inflammatory activity of the bark of Eysenhardtia polystachia in experimental animal models 

              (May 25, 2011) Anti-inflammatory properties from isolated compounds of Cyclolepis genistoides 

              (Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae) 

               

               

               

              Flavonoids

               

              (2012) Flavonoid intake and bone health

              (2009) Chapter 18 -  Flavonoids and Cardiovascular Health

              (2016, Dec 29) (Medical Review: 161 studies) Flavonoids: an overview 

              (2013, Dec 29) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview

              (2003) Lupin

              (2014) Chapter 23 - The Role of Direct and Indirect Polyphenolic Antioxidants in Protection Against Oxidative Stress 

              (2014) Polyphenols in Chronic Diseases and their Mechanisms of Action

              (2014) Antioxidant Properties of Wheat Bran against Oxidative Stress

              (2014)  Chapter 32 - Anti-Inflammatory and Immunomodulatory Properties of Dietary Flavonoids

              (2010) Chemistry of Cannabis

              (2012) Habitual intake of dietary flavonoids and risk of Parkinson disease 

              (2013, Feb) Dietary flavonoids and the development of type 2 diabetes and cardiovascular diseases: review of recent findings. 

              (2016) Dietary flavonoid intake and incidence of erectile dysfunction 

              (2012) Flavonoids and cancer prevention: a review of the evidence.

              (2001) Dietary agents in cancer prevention: flavonoids and isoflavonoids. 

              (2005) The antitumor activities of flavonoids. 

              (2018) Dietary Flavonoids and the Risk of Colorectal Cancer: An Updated Meta-Analysis of Epidemiological Studies. 

              (2019) Association between flavonoids, flavonoid subclasses intake and breast cancer risk: a case-control study in China.

              (2019) Flavonoids and bladder cancer risk.

              (2019) Flavonoids and bladder cancer risk

               

               

              Diuretic

              (Jul-Sep, 2002) Effect of isoflavones isolated from heartwood of Eysenhardtia polystachya on the growth of oxalate crystals and urinary calcium phosphate

              (Jan 21, 2016) Diuretic activity of the bark of Eysenhardtia polystachya

              (2006) Herbal medicine of the American Southwest : a guide to the medicinal and edible plants of the Southwestern United States

              (June 28, 2007) Estudio Etnobotánico de Eysenhardtia Polystachia (Ort.) Sarg. En una Comunidad del Municipio de Zempola, Hidalgo, y Evaluación del Efecto Diurético en Rata

              (Feb, 2009) Activity of extracts from two Eysenhardtia species against microorganisms related to urinary tract infections

              (Jul 2004) Effect of isoflavones from Eysenhardtia polystachya as inhibitors of calcium oxalate crystal aggregation 

              (Jan-May, 2007) Herbal Drugs in Urolithiasis - A Review

              (Dec 18, 1998) Antiurolithiatic activity of Eysenhardtia polystachya aqueous extract on rats

              Palo Azul (Cyclolepis Genistoides)

              (Oct 22, 2008) Antiurolithiatic Activity of 7-Hydroxy-2,4,5- Trimethoxyisoflavone and 7-Hydroxy-4 -Methoxyisoflavone from Eysenhardtia polystachya

               

               

               

              Anti-Diabetic

              (May 1, 2018) Protection of silver nanoparticles using Eysenhardtia polystachya in peroxide-induced pancreatic β-Cell damage and their antidiabetic properties in zebrafish

              (Nov 2013) Cyclolepis genistoides D. Don (palo azul) promotes differentiation of adipocytes and regulates adipokine expression

              (July 2016) Ethanol extract of Cyclolepis genistoides D. Don (palo azul) induces formation of myotubes, which involves differentiation of C2C12 myoblast cells

              (Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models 

              (March 16, 2001) Antihyperglycemic Activity and Chemical Constituents of Eysenhardtia platycarpa

               

               

               

              Antiviral & Antibacterial


              (Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae)

              (June 14, 2012) Ethnobotanical survey and antibacterial activity of plants used in the Altiplane region of Mexico for the treatment of oral cavity infections

              ACTIVIDAD ANTIMICROBIANA DE LOS EXTRACTOS DE Eysenhardtia polystachya texana


               




              Sciatic Nerve, Back Pain and Arthritis


                (Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models

                (Feb 29, 2015) Evolution of anti-inflammatory activity of the bark of Eysenhardtia polystachia in experimental animal models

                (May 25, 2011) Anti-inflammatory properties from isolated compounds of Cyclolepis genistoides 

                (Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae) 

                (2012) Flavonoid intake and bone health

                (2010) Transgenic inhibition of glial NF-kappa B reduces pain behavior and inflammation after peripheral nerve injury

                (2019) Sciatica Nerve Pain

                (2008) Development of a capillary electrophoresis method for the characterization of “palo azul” (Eysenhardtia polystachya)

                (Feb 29, 2015) Evolution of anti-inflammatory activity of the bark of Eysenhardtia polystachia in experimental animal models

                (May 25, 2011) Anti-inflammatory properties from isolated compounds of Cyclolepis genistoides 

                (Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae) 

                 





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                If you’re reading this, I have to say I’m impressed! Feel free to text me at 754-422-3361 and ask me anything…like how long it took me to write this perhaps. I’ll probably send you some free palo azul since I can see you like it so much!

                - Julian Tcherassi