Palo Azul vs Arthritis and Back Pain

woman with back pain

Studies show that palo azul can help treat arthritis and back pain

Research shows that palo azul tea has been proven to be effective for healing lower back and joint pains.

Two studies found that palo azul was effective in treating arthritic rats. Moreover, studies concluded that palo azul’s flavonoids and anti-inflammatory capabilities are effective for treating arthritis and pain management. 

omega 3 antiinflammatory

Six different studies concluded in their results that palo azul induced a significant inhibition of inflammation and/or showed anti-inflammatory activity. Moreover, several studies show that “extracts in palo azul act as anti-inflammatory agents.”

Here's a list of some of the most anti-inflammatory foods: vegetables, fruits, nuts, seeds, fatty fish, olive oil, turmuric, cocoa and teas such as palo azul

palo azul and antiinflammatory foods

In fact, a study found that flavonoids (found in vegetables, fruits and teas like palo azul) “have the most potential of dietary components for promotion of bone health beyond calcium and vitamin D.”

This finding is supported by population studies whichecent have shown “flavonoid consumption to have a stronger association with bone than general fruit and vegetable consumption.”

palo azul strengthens joint health

This same study which found that “palo azul and its flavonoids-rich fractions inhibited secondary inflammatory reactions in arthritic rats” also concluded that “many plant constituents, including flavonoids, have proven effective against arthritis.”

Another study mentions that many plant constituents, including flavonoids, have proven effective against arthritis by reducing cartilage degradation, diminishing leukocyte infiltration in the synovial space, decreasing serum cytokine levels, and other mechanisms (9).“

These are the most flavonoid-rich foods: apples, pears, onions, strawberries, blueberries, celery, peppers, and teas such as palo azul

applepearsonionsstrawberries and blueberriescelerypalo azul tea


Antinociceptive

Several studies have also shown that palo azul has antinociceptive properties. What does this mean? Antinociceptives block the detection of a painful or harmful stimulus by sensory neurons. 

In other words... they inhibit the sensation of pain by blocking signals from neurons. Popular examples of antinociceptives include general anesthesia and morphine.

One study mentioned that palo azul “decreased the serum levels of pro-inflammatory cytokines and showed antinociceptive activity. These findings support the use of Eysenhardtia polystachya in Mexican folk medicine for treating rheumatoid arthritis and pain management.

Here's an interesting finding: A study found that palo azul “showed antinociceptive and antidiarrheal effects with similar potency compared to standard drugs.”

* Although we do not recommend replacing standard medications, these findings establish the importance of having a diet full of natural medicines with potent health benefits. 

palo azul and fruits with flavonoids

For all these reasons palo azul has been used traditionally for centuries to treat conditions such as arthritis, rheumatism, lumbago, gout and sciatica.

Below, we have summarized the key points of all the medical studies we have analyzed and also cited all the scientific literature.

book with palo azul benefits and studies

Key findings from medical studies


• “PAM (palo azul) possesses significantly dose-related antiarthritic activity in M. tuberculosis-induced adjuvant arthritis test in rat, which is considered close to simulating human rheumatoid arthritis.”

• Flavonoids “have been reported to enhance bone formation and to inhibit bone resorption through their action on cell signaling pathways that influence osteoblast and osteoclast differentiation.”

• “Our data indicate that PAM (palo azul) exhibited significant anti-inflammatory activity in all the trials of paw and ear edema induced exhibiting also anti-arthritic activity.”

• “Palo azul (C. genistoides) showed a significant inhibition of the carrageenan-induced inflammation at doses of 75 and 100 mg/kg. These results give support to the use of this plant as an anti-inflammatory in traditional medicine.”

    •“We evaluated the anti-arthritic and antinociceptive properties of an ethanolic extract of E. polystachya (EE) bark and its rich-flavonoids fractions in murine models. Many plant constituents, including flavonoids, have proven effective against arthritis by reducing cartilage degradation, diminishing leukocyte infiltration in the synovial space, decreasing serum cytokine levels, and other mechanisms (9).“ 

    • “The results here presented corroborate the folk medicinal use of Eysenhardtia polystachya in the treatment of infections, diarrhea, inflammation, and pain.” 

       

      magiktea palo azul logo

      Don't keep the magic to yourself though...
      share palo azul with your loved ones!
       
       
       

      Medical Studies

      * Palo Azul is commonly referred to by its scientific name: Eysenhardtia polystachya / E. polystachya / E.P - Cyclolepis genistoides / C. genistoides - kidney wood - palo dulce


      (Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models

      (2013, Dec 29) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview 

      (May 25, 2011) Anti-inflammatory properties from isolated compounds of Cyclolepis genistoides 

      (Feb 29, 2015) Evolution of anti-inflammatory activity of the bark of Eysenhardtia polystachia in experimental animal models

      (2012) Flavonoid intake and bone health

      (2009) Chapter 18 -  Flavonoids and Cardiovascular Health

      (2016, Dec 29) (Medical Review: 161 studies) Flavonoids: an overview 

      (Dec 1, 2011) SEPARACIÓN Y EVALUACIÓN DEL EFECTO ANTIINFLAMATORIO Y ANTIOXIDANTE DE LOS FLAVONOIDES DE Eysenhardtia polystachya (Ort.) Sarg. 

      (Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae) 

      (2013, Dec 29) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview 

      (2003) Lupin

      (2014) Chapter 23 - The Role of Direct and Indirect Polyphenolic Antioxidants in Protection Against Oxidative Stress 

      (2014)  Chapter 32 - Anti-Inflammatory and Immunomodulatory Properties of Dietary Flavonoids