Studies Show Palo Azul's Beneficial Effects on Hypertension

man with hypertension

"Flavonoids are associated with a lower risk of hypertension"

In addition to all the other beneficial properties of palo azul, this magical tea also has one of the most well studied and healthful compounds in the world... Flavonoids! 

You’ve probably heard of the antioxidant health benefits of green tea and how they may help promote weight loss, healthy levels of blood pressure, cholesterol, etc. Many studies have actually attributed these beneficial effects to the flavonoids in green tea.

What are flavonoids?

palo azul and antioxidant fruits

Flavonoids are phytonutrients which plants produce in order to fight off infections, oxidative stress, and inflammation. They're commonly found in vegetables, fruits, plants, bark, flowers, wine and teas such as palo azul.

2021 study even found several phytochemicals in palo azul such as “flavones, isoflavones, flavanones, phenolic compounds, chalcones and dihydrochalcones” which have been linked to its health benefits, highlighting “diuretic, antidiabeticantiglycationantioxidant, anti-inflammatory, antimicrobial potential.”

polyphenols flavonoids family treeThat's great news for palo azul tea lovers because thousands of studies have found that flavonoids are anti-oxidant, anti-inflammatory, anti-diabetic, anti-aging, anti-hypertensive, anti-bacterial and anti-mutagenic. 


1. Promote healthy blood pressure

Woman measuring blood pressure

According to the findings of two medical reviews (1) (2composed of findings from 327 different studies conducted specifically on flavonoids, "dietary flavonoids are associated with a lower risk of hypertension and CVD (cardiovascular disease).” 

The researchers also observed that “the blood pressure level was reduced in patients with hypertensionafter greater consumption of flavonoids. Moreover, they found that flavonoids in tea may “lower blood cholesterol concentrations and blood pressure, thereby providing some protection against cardiovascular disease.” 

2010 study which supports these results, found that "polyphenolic compounds (flavonoids) have demonstrated their inhibitory effects against chronic vascular inflammation associated with atherosclerosis."


2. Scavenge free radicals

palo azul vs free radicals

The scientists who published these reviews also found that "flavonoids can prevent injury caused by free radicals in various ways and one way is the direct scavenging of free radicals. This action protects the LDL particles and, theoretically, flavonoids may have preventive action against atherosclerosis.”

One of the previously cited medical reviews also found that flavonoids “inhibit LDL oxidation via a mechanism involving scavenging of free radicals.” The researchers mention that “oxidative modification of LDL cholesterol is thought to play a key role during atherosclerosis."

What are free radicals?

Free radicals are atoms with a single valence electron that cause damage to the body associated with diabetes, cancer, aging, atherosclerosis, Parkinson's, Alzheimer's and many other diseases.

free radicals and oxidative stress formation

This happens because electrons like to be in pairs... and for this reason, free radicals look for "free" electrons in the body. This causes damage to cells, proteins, DNA and these damaged molecules can mutate, grow tumors, and damage the DNA code. Eventually, this cellular damage causes new cells to grow with defects and it will lead to aging and degenerative diseases. 


3. Improve endothelial function

heart blood pressure

The researchers also observed that the “consumption of them (flavonoids) is associated with improvement in endothelial function via vascular endothelial nitric oxide synthase and protein kinase B (Akt) activation.”

2012 study explains the biological mechanisms of flavonoids beneficial effects on cardiovascular disease:
“Studies have indicated the protective effects of flavonoids in cardiovascular diseases and these chemicals possess the bioactivity to positively affect against cardiovascular risk factors such as lipoprotein oxidation, dyslipidemia and endothelial dysfunction.

Lipoprotein oxidation triggers inflammation leading to the formation of plaque in the arteries, also known as atherosclerosis. Oxidized LDL may also play a role in increasing the amount of triglycerides the body produces, as well as increasing the amount of fat deposited by the body.

Dyslipidemia is elevation of plasma cholesterol and triglycerides that contribute to the development of atherosclerosis.

In other words...flavonoids can help to inhibit oxidation and inflammation which can cause blockage in the arteries, thereby lowering triglycerides and fat storage.

What is endothelial dysfunction?

palo azul vs endothelial dysfunction or clogged arteries

The endothelium is a thin membrane that lines the inside of the heart and blood vessels. Endothelial cells release substances that control vascular relaxation and contraction, as well as enzymes that control blood clotting, immune function, and platelet adhesion.

Endothelial dysfunction has been shown to be important in predicting stroke and heart attacks due to the inability of the arteries to dilate completely. Dysfunction can result from high blood pressure, diabetes, high cholesterol, and smoking.

2020 study explains that "endothelial function is a metric that reflects the production of endothelium-derived messengers that control vascular tone, blood flow, immune cell activity and adhesion, all of which play a role in regulating blood pressure." In other words...Healthy endothelial function = Cardiovascular health.

blood pressure meter

Finally, one of the medical reviews concludes that “a diet rich in all flavonoid classes through herbs and beverages improves vascular health leading to a reduced risk of diseases.”


In summary, palo azul may help to promote heart health because it's antioxidant and it's rich in flavonoids. Flavonoids can help to promote healthy levels of blood pressure, cholesterol, well as reduce inflammation, inhibit lipoprotein oxidation and scavenge free radicals which can cause blockage in the arteries. Therefore, palo azul tea could have beneficial effects on endothelial function and hypertension.  

P.S...Don't keep this to yourself, share these tips with your loved ones!

Flavonoid-rich foods: apples, pears, onions, strawberries, blueberries, celery, peppers, and teas

applepearsonionsstrawberries and blueberriescelerypalo azul tea cup


    magiktea palo azul logo

     Start scavenging those free radicals...
    and stop lipoprotein oxidation! 😉


    Clinical Studies

    * Palo azul is commonly referred to by its scientific name: Eysenhardtia polystachya / E. polystachya / E.P - Cyclolepis genistoides / C. genistoides - kidney wood - palo dulce


    (October 2021) Minocycline-Derived Silver Nanoparticles for Assessment of Their Antidiabetic Potential against Alloxan-Induced Diabetic Mice

    (August 2021) Screening Anti-Inflammatory Effects of Flavanones Solutions

    (2013) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview

    (2016) (Medical Review: 161 studies) Flavonoids: an overview 

    (2014) Evaluation of antidiabetic, antioxidant and antiglycating activities of the Eysenhardtia polystachya

    (2010) Polyphenols and Aging

    (2009) Chapter 18 -  Flavonoids and Cardiovascular Health