Palo azul vs Joint Pain

woman doing strength exercise

Studies show that palo azul can relieve joint pain

You might be thinking…”How can drinking tea strengthen my joints and relieve joint pain?” We thought the same thing, so we did a ton of research and found 2 main reasons: Inflammation and flavonoids

omega 3 antiinflammatories and flavonoids

Six different studies concluded in their results that palo azul induced a significant inhibition of inflammation and/or showed anti-inflammatory activity. Moreover, several studies show that “extractis in palo azul act as anti-inflammatory agents.”

palo azul anti-inflammatory


A common cause of joint pain is inflammation...and many studies have proven palo azul’s powerful anti-inflammatory activity.

Antiinflammatory and antioxidant foods: vegetables, fruits, nuts, seeds, fatty fish, olive oil, turmuric, cocoa and teas such as palo azul

palo azul and antiinflammatory foods

Hundreds of studies have shown that palo azul and its flavonoids are powerful anti-inflammatories and because of this property, their ability to calm joint pain has been demonstrated.


palo azul flavonoids


Astudy found that flavonoids (found in vegetables, fruits and teas like palo azul) “have the most potential of dietary components for promotion of bone health beyond calcium and vitamin D.”

palo azul strengthens joint health

This finding is supported by population studies which have shown “flavonoid consumption to have a stronger association with bone than general fruit and vegetable consumption.”

palo azul antinociceptive


Several studies have also shown that palo azul has antinociceptive properties. What does this mean? Antinociceptives block the detection of a painful or harmful stimulus by sensory neurons. 

In other words... they inhibit the sensation of pain by blocking signals from neurons. Popular examples of antinociceptives include general anesthesia and morphine.

One study mentioned that palo azul “decreased the serum levels of pro-inflammatory cytokines and showed antinociceptive activity. These findings support the use of Eysenhardtia polystachya in Mexican folk medicine for treating rheumatoid arthritis and pain management.

Here's an interesting finding: Another study found that palo azul “showed antinociceptive and antidiarrheal effects with similar potency compared to standard drugs.”

* Although we do not recommend replacing standard medications, these findings establish the importance of having a diet full of natural medicines with potent health benefits. 

palo azul and fruits with flavonoids


For these 3 reasons, palo azul has traditionally been used for joint pain, arthritis, sciatica, gout and low back pain for centuries!

Below we have outlined the key points from all of the research we’ve done and we’ve also cited all of the research literature.

P.S...Don’t forget to help your loved ones by sharing palo azul with them!

book with palo azul benefits and studies

Key findings from medical studies

• Numerous studies have shown that palo azul is anti-inflammatory and due to this property, research has proven its ability to calm joint pain.

• Flavonoids “have been reported to enhance bone formation and to inhibit bone resorption through their action on cell signaling pathways that influence osteoblast and osteoclast differentiation.”

• Flavonoids (found in vegetables, fruits and teas like palo azul) “have the most potential of dietary components for promotion of bone health beyond calcium and vitamin D.”

“Eysenhardtia polystachya (palo azul) is used for the empirical treatment of cancer, infections, diarrhea, inflammation, and pain.”

• “We evaluated the anti-arthritic and antinociceptive properties of an ethanolic extract of E. polystachya (EE) bark and its rich-flavonoids fractions in murine models. Many plant constituents, including flavonoids, have proven effective against arthritis by reducing cartilage degradation, diminishing leukocyte infiltration in the synovial space, decreasing serum cytokine levels, and other mechanisms (9).“

• “The results here presented corroborate the folk medicinal use of Eysenhardtia polystachya (Palo Azul) in the treatment of infections, diarrhea, inflammation, and pain.”

magiktea palo azul logo

Pretty magical right? ;)

Medical Studies

* Palo Azul is commonly referred to by its scientific name: Eysenhardtia polystachya / E. polystachya / E.P - Cyclolepis genistoides / C. genistoides - kidney wood - palo dulce

(2012) Flavonoid intake and bone health

(Winter 2018) The Ethanolic Extract of Eysenhardtia polystachya (Ort.) Sarg. Bark and Its Fractions Delay the Progression of Rheumatoid Arthritis and Show Antinociceptive Activity in Murine Models

(2013, Dec 29) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview 

(May 25, 2011) Anti-inflammatory properties from isolated compounds of Cyclolepis genistoides 

(Feb 29, 2015) Evolution of anti-inflammatory activity of the bark of Eysenhardtia polystachia in experimental animal models

(2009) Chapter 18 -  Flavonoids and Cardiovascular Health

(2016, Dec 29) (Medical Review: 161 studies) Flavonoids: an overview 


(Oct, 2018) Pharmacological and toxicological study of a chemical-standardized ethanol extract of the branches and leaves from Eysenhardtia polystachya (Ortega) Sarg. (Fabaceae) 

(2013, Dec 29) (Medical review: 166 studies) Chemistry and Biological Activities of Flavonoids: An Overview 

(2003) Lupin

(2014) Chapter 23 - The Role of Direct and Indirect Polyphenolic Antioxidants in Protection Against Oxidative Stress 

(2014)  Chapter 32 - Anti-Inflammatory and Immunomodulatory Properties of Dietary Flavonoids